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Can I take Adcal-D3 and Collagen together?

Drug interaction guide

There is no known harmful interaction between Adcal-D3 and collagen supplements. In fact, they are often used together to support bone and joint health.

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Why this happens

Adcal-D3 provides calcium and vitamin D3, while collagen provides amino acids. These substances are processed by the body through different pathways and do not interfere with each other's absorption or effectiveness.

You can safely take these together. For the best absorption of the calcium in Adcal-D3, it is usually recommended to take it with or after a meal. Collagen can be taken at the same time.

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Kidney stones or severe kidney disease

Do not take Adcal-D3 if you have a history of kidney stones or severe kidney impairment, as it can increase the risk of further stone formation and cause calcium to build up to dangerous levels in your blood.

High blood calcium (Hypercalcaemia)

You must not take Adcal-D3 if you have been told you have high levels of calcium in your blood or urine (often caused by overactive parathyroid glands or certain bone cancers), as it can lead to heart rhythm problems or kidney damage.

Caffeine (Tea, Coffee, Cola)

Caffeine can reduce the amount of calcium your body absorbs. It is best to limit high caffeine intake or avoid having these drinks at the same time as your supplement.

Foods high in Oxalic Acid or Phytic Acid (Spinach, Rhubarb, Whole-grain cereals)

These foods can bind to calcium and prevent it from being absorbed properly. You should wait at least 2 hours after eating these foods before taking your Adcal.

Dairy products

While dairy contains calcium, consuming very large amounts of dairy alongside calcium supplements (Adcal) can occasionally lead to 'milk-alkali syndrome'. Maintain a balanced diet and do not excessively exceed recommended calcium intakes.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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