Can I take Alogliptin and Bisoprolol together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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Taking bisoprolol with alogliptin may occasionally hide the warning signs of low blood sugar (hypoglycaemia). It can also slightly increase the risk of your blood sugar dropping too low.
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Why this happens
Bisoprolol is a beta-blocker. These medicines can mask the physical symptoms of low blood sugar, such as a fast heartbeat or tremors. Additionally, beta-blockers can sometimes interfere with how the body releases glucose, which may enhance the blood-sugar-lowering effect of alogliptin.
What you should do
Back to contentsYou can take these medicines together, but you should be aware that you might not feel the usual 'shaky' or 'racing heart' sensations if your blood sugar drops. Pay closer attention to other signs of low blood sugar, such as sweating, hunger, or blurred vision. Monitor your blood glucose levels regularly as advised by your doctor.
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Important precautions
Back to contentsAsthma or Chronic Obstructive Pulmonary Disease (COPD)
Bisoprolol can cause narrowing of the airways, which may trigger a severe asthma attack or worsen breathing difficulties. Ensure your doctor knows if you have a history of wheezing.]
Acute Pancreatitis
Stop taking alogliptin and seek immediate medical help if you experience severe and persistent stomach pain, which may reach through to your back, as this can be a sign of an inflamed pancreas.
Food and drink warnings
Back to contentsAlcohol
Drinking alcohol can increase the blood-pressure-lowering effect of bisoprolol, which may make you feel dizzy or light-headed, especially when you first start taking it or if your dose is increased. It is best to keep your alcohol intake within recommended limits and see how the medicine affects you before drinking.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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