Can I take Atorvastatin and Losartin together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There is no significant interaction between atorvastatin and losartan. These two medicines are very commonly prescribed together to manage high blood pressure and high cholesterol.
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Why this happens
Atorvastatin and losartan are processed by different pathways in the liver and do not interfere with how the body absorbs or removes each other. They also work on different systems (cholesterol vs. blood pressure) without causing harmful additive effects.
What you should do
Back to contentsYou can safely take these medicines together as prescribed by your doctor. It is usually best to take them at the same time each day to help you remember. Always inform your doctor if you experience unusual muscle pain or weakness, which is a rare side effect of statins, but this is not caused by taking losartan.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Can I take Amlodipine and Simvastatin together?
Taking these two medicines together can increase the amount of simvastatin in your blood. This makes you more likely to experience side effects, particularly muscle pain, tenderness, or weakness (a condition called myopathy). In rare cases, this can lead to a serious condition called rhabdomyolysis, which can cause kidney damage.

Treatment and medication
Can I take Amlodipine and Tramadol together?
Taking these two medicines together can cause your blood pressure to drop lower than intended. This might make you feel dizzy, lightheaded, or faint, especially when standing up quickly. There is also a small risk that tramadol could slightly interfere with how amlodipine is processed in your body, though the main concern is the combined effect on your blood pressure and heart rate.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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