Can I take Atorvastatin and Metformin together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no significant direct interaction between atorvastatin and metformin. Both medications are commonly prescribed together to manage cholesterol and blood sugar levels in patients with type 2 diabetes.
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Why this happens
Atorvastatin and metformin are processed by different pathways in the body. Atorvastatin is primarily broken down by the liver (CYP3A4 enzyme), while metformin is cleared by the kidneys. They do not interfere with each other's absorption or metabolism.
What you should do
Back to contentsYou can safely take these medications together as prescribed by your doctor. It is important to continue taking both to manage your heart health and blood sugar levels. If you experience unusual muscle pain or weakness (a rare side effect of statins), you should still report this to your doctor.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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