Can I take Devil's claw and Turmeric with black pepper together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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Taking devil's claw and turmeric together may increase the risk of bruising or bleeding. Both supplements can also lower blood sugar levels, which might cause them to drop too low if you are sensitive or taking diabetes medication. Additionally, both can increase stomach acid, potentially causing stomach upset or irritation.
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Why this happens
Both devil's claw and turmeric have mild 'blood-thinning' properties (antiplatelet effects), which can have an additive effect when combined. They also both possess glucose-lowering properties. The black pepper (piperine) in the turmeric supplement is designed to significantly increase the absorption of turmeric, which may also inadvertently increase the absorption or slow the breakdown of devil's claw in the liver.
What you should do
Back to contentsUse this combination with caution. If you notice unusual bruising, nosebleeds, or bleeding gums, stop taking them and consult your doctor. If you have diabetes, monitor your blood sugar levels closely. It is best to take these supplements with food to protect your stomach. Always inform your doctor or pharmacist before starting these supplements if you are taking prescribed blood thinners (like warfarin) or stomach acid reducers.
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Important precautions
Back to contentsGallstones or bile duct obstruction
Both medicines stimulate bile production. If you have gallstones or a blocked bile duct, this can cause a painful gallbladder attack or worsen the blockage.
Stomach or duodenal ulcers
Devil's claw increases the production of stomach acid, which can severely irritate or worsen existing stomach or intestinal ulcers.
Blood-thinning medications (e.g., warfarin, clopidogrel)
Turmeric and black pepper can both thin the blood. Taking them with prescribed anticoagulants significantly increases your risk of serious bruising or internal bleeding.
Food and drink warnings
Back to contentsAlcohol
Devil's claw can increase the production of stomach acid. Combining it with alcohol, which also irritates the stomach lining, may increase the risk of stomach upset or gastric ulcers.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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