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Can I take Furosemide and Joint assurance together?

Drug interaction guide

Taking furosemide with Joint Assurance (which contains glucosamine and chondroitin) may increase the risk of bruising or bleeding if you are also taking blood-thinning medication. Additionally, glucosamine can sometimes affect blood sugar levels, which may interfere with how well furosemide works for certain patients.

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Why this happens

Glucosamine and chondroitin (found in Joint Assurance) can enhance the effects of blood-thinning medications. While they do not directly change how furosemide works in the body, the combination can occasionally lead to changes in blood sugar or blood pressure stability in sensitive individuals.

You may be experiencing an interaction between furosemide and joint assurance if:

  • You feel dizzy or lightheaded, particularly when standing up.

  • You notice increased tiredness or weakness.

  • You develop muscle cramps or muscle weakness, which may be linked to electrolyte changes.

  • You experience changes in swelling in your legs or joints.

  • You notice digestive symptoms, such as nausea or stomach upset.

  • Blood tests show changes in kidney function or electrolyte levels.

  • Symptoms start after starting the supplement or changing the dose while taking furosemide.

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It is generally safe to take these together, but you should monitor your blood pressure regularly. If you notice any unusual bruising, bleeding, or a significant change in your blood sugar levels, speak to your GP or pharmacist.

If you have any of the above symptoms, you should:

  • Contact your GP or pharmacist for advice as soon as possible.

  • Do not stop taking furosemide suddenly unless advised by a healthcare professional.

  • Avoid starting, stopping, or changing Joint Assurance or other supplements without medical advice.

  • Seek urgent medical help if you experience severe dizziness, confusion, or muscle weakness.

  • Attend any blood tests arranged to check kidney function or electrolyte levels.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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