Can I take Glucosamine and Magnesium together?
Drug interaction guide
Originally published 25 Jan 2026
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There are no known significant interactions between glucosamine and magnesium when taken together. Both are commonly used supplements that work in different ways within the body.
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Why this happens
Glucosamine is an amino sugar used by the body to build cartilage, while magnesium is a mineral involved in over 300 enzyme reactions, including muscle and nerve function. They do not share the same metabolic pathways in the liver, nor do they interfere with each other's absorption in the digestive tract.
What you should do
Back to contentsIt is generally safe to take these two supplements together. However, always follow the dosage instructions on the packaging. If you have pre-existing kidney disease or are taking blood-thinning medication (like warfarin), you should consult your doctor or pharmacist before starting any new supplements.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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