Can I take Metformin and Sertraline together?

Why this happens

Sertraline belongs to a group of medicines called SSRIs, which can change how the body handles glucose and may increase the body's sensitivity to insulin. While the exact way they interact with metformin isn't fully understood, it is known that starting or stopping an antidepressant can cause fluctuations in blood sugar control.

You can take these medicines together, but you should monitor your blood sugar levels more closely when you first start sertraline or if your dose changes. If you notice signs of low blood sugar (such as feeling shaky, sweaty, hungry, or confused), treat it as usual and inform your doctor. Do not change your metformin dose without medical advice.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.