Can I take Anastrozole and Venlafaxine krka together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There is no known direct interaction between anastrozole and venlafaxine. It is generally considered safe to take these two medications together.
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Why this happens
Anastrozole is an aromatase inhibitor used to treat breast cancer, and venlafaxine is an antidepressant (SNRI). They are processed by different pathways in the liver and do not interfere with each other's effectiveness or increase the risk of side effects. Unlike some other antidepressants (such as fluoxetine or paroxetine), venlafaxine does not block the enzymes needed for breast cancer treatments to work.
What you should do
Back to contentsYou can continue taking both medications as prescribed. However, always inform your doctor or pharmacist if you notice any new or worsening side effects, such as increased hot flushes, nausea, or changes in mood.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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