Can I take Aspirin and Boots ibuprofen together?

Why this happens

Both drugs belong to a group called NSAIDs. They work by blocking the same enzymes (COX-1 and COX-2). When taken together, they have an 'additive' effect on the stomach lining, making damage more likely. Furthermore, ibuprofen can physically block aspirin from attaching to blood cells (platelets), which prevents aspirin from thinning the blood effectively.

You should avoid taking these two medicines together. If you take daily low-dose aspirin for your heart, speak to your doctor or pharmacist before taking ibuprofen. They may suggest an alternative painkiller like paracetamol. If you must take both, take the aspirin at least 30 minutes before the ibuprofen, or wait 8 hours after taking ibuprofen before taking your aspirin.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.