Can I take Gabapentin and Zapain together?

Why this happens

Both gabapentin and the codeine in Zapain act as central nervous system (CNS) depressants. This means they both slow down brain activity and the signals that control breathing and alertness. When used together, they have an 'additive effect', meaning their combined impact is much stronger than taking either drug alone.

You may be experiencing an interaction between gabapentin and zapain if:

• You feel excessively drowsy, sleepy, or sedated.

• You experience dizziness, confusion, or difficulty concentrating.

• You notice trouble with coordination or balance, increasing the risk of falls.

• You develop constipation or difficulty passing urine.

• You experience nausea or vomiting.

• Symptoms appear shortly after taking both medicines together.
  

You must speak to your doctor before taking these medicines together. If your doctor prescribes both, they will likely start you on the lowest possible doses and monitor you closely. Do not drive or operate machinery until you know how this combination affects you. Seek urgent medical help if you experience extreme sleepiness, confusion, or difficulty breathing. Avoid alcohol entirely, as it will make these dangerous side effects much worse.

If you have any of the above symptoms, you should:

• Speak to your GP or pharmacist for advice on safe use and dosing.

• Do not stop gabapentin or Zapain suddenly unless instructed by a healthcare professional.

• Seek urgent medical help if you experience severe drowsiness, difficulty breathing, or persistent vomiting.

• Avoid driving or operating machinery until you know how the combination affects you.

• Tell your healthcare professional about all other medicines and supplements you are taking.
  

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.