Can I take Mirtazapine and Sukkarto together?
Drug interaction guide
Originally published 25 Jan 2026
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Mirtazapine may occasionally cause changes in blood sugar levels or lead to weight gain, which could make it slightly harder for Sukkarto (metformin) to control your diabetes. However, most people can take these two medicines together safely.
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Why this happens
Mirtazapine can cause an increase in appetite and weight gain in some patients. Because weight and diet directly affect blood sugar levels, this can indirectly interfere with how well Sukkarto (metformin) manages your diabetes. There is also a very small risk that mirtazapine could directly affect how the body handles glucose.
What you should do
Back to contentsYou can take these medicines together, but you should monitor your blood sugar levels more closely when you first start mirtazapine or if your dose changes. If you notice your blood sugar readings are consistently higher than usual, or if you find it difficult to manage your weight, speak with your doctor or diabetic nurse. They may need to adjust your diabetes medication or offer dietary advice.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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