Can I take Pregabalin and Vitamin d together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
There are no known significant interactions between pregabalin and vitamin D supplements. It is generally considered safe to take these two together.
In this article:
Continue reading below
Why this happens
Pregabalin and vitamin D are processed by the body using different pathways. Pregabalin is mainly removed from the body by the kidneys and does not interfere with the liver enzymes that process vitamin D. Furthermore, they do not have overlapping side effects that would cause concern.
What you should do
Back to contentsYou can continue to take both as prescribed. As with any supplement, it is always a good idea to inform your doctor or pharmacist about everything you are taking to ensure your records are up to date.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Alcohol and Amitriptyline together?
Combining alcohol with amitriptyline can make you feel much more drowsy, dizzy, and unsteady than usual. It can also significantly slow down your reaction times and impair your coordination. In some cases, it can lead to more serious issues like extreme confusion, difficulty breathing, or fainting.

Treatment and medication
Can I take Amitriptyline and Shortec together?
Taking amitriptyline and Shortec (oxycodone) together can make you feel very drowsy, dizzy, and confused. It can also significantly slow down your breathing and heart rate, which can be dangerous. You may also experience increased side effects like a very dry mouth, constipation, and difficulty passing urine.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.