Can I take Ripinrole and Shortec together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
Taking ropinirole and Shortec (oxycodone) together can make you feel very sleepy, dizzy, or confused. It can also slow down your breathing and make you feel faint when you stand up.
In this article:
Continue reading below
Why this happens
Both medicines affect the brain and central nervous system. Ropinirole is a dopamine agonist and Shortec is an opioid painkiller. When used together, their sedative effects add up, making the side effects of both drugs much stronger.
What you should do
Back to contentsUse this combination with great caution. Do not drive or operate machinery until you know how these medicines affect you. Avoid alcohol, as it will make the sleepiness much worse. If you feel extremely drowsy or have trouble breathing, seek medical help immediately. Your doctor may need to adjust your doses.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions
Treatment and medication
Can I take Amlodipine and Rybelsus together?
Taking Rybelsus (semaglutide) alongside amlodipine may occasionally lead to a further drop in blood pressure. While Rybelsus is primarily for blood sugar, it can sometimes cause a slight reduction in blood pressure or a small increase in heart rate. When combined with a blood pressure medicine like amlodipine, you might feel slightly more dizzy or lightheaded, especially when standing up quickly.
Treatment and medication
Can I take Amlodipine and Danazol together?
Taking danazol while you are on amlodipine can cause the levels of amlodipine in your blood to rise. This can lead to an increased risk of side effects, such as feeling dizzy, getting a headache, or experiencing swelling in your ankles (oedema). It may also cause your blood pressure to drop lower than intended.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.
Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.